• Chemical Exchange Saturation Transfer (CEST) imaging of oncolytic virotherapy using a herpes simplex virus (G47Δ) engineered to express a lysine rich protein (LRP) CEST reporter gene.

​About the Lab
Our research is focused on the development of new Magnetic Resonance molecular imaging methods and contrast agents. The tools being developed in our lab are being applied to studies of a wide range of diseases, including Alzheimer’s disease, cancer, liver fibrosis, and stroke. Our recent molecular imaging efforts have been focused on the development of chemical exchange saturation transfer (CEST) MRI reporter genes for imaging oncolytic virotherapy, deep learning based CEST magnetic resonance fingerprinting (MRF) methods for rapid and quantitative CEST imaging of brain tumors and stroke, collagen targeted MRI contrast agents for imaging liver fibrosis, and RNA aptamer probes for imaging amyloid-β plaques.